Dr in Physiology, Researcher, Prof. (adj.) affiliated to the Dpt of Medicine, Faculty of Medicine, UdeM.
Prof. Accredited : a) Dpt of Physiology and Pharmacology, Faculty of Medicine, b) Prog. of Biomedical Sciences, Dpt of Medicine,UdeM
Dr. Roddy Hiram obtained his doctorate in 2016, at the Faculty of Medicine and Health Sciences of the University of Sherbrooke. He then received postdoctoral training in cardiology at the University of Montreal.
Since 2021, at the Montreal Heart Institute, Dr. Roddy Hiram's research focuses on cardiac arrhythmias, particularly atrial fibrillation, in the context of right heart failure. Specifically, he studies the impact of inflammation and its resolution in developing cardiac arrhythmogenic remodelling.
The main scientific aims of his lab include:
1. In vitro description of the activation of inflammation at the molecular and cellular level, suspected of promoting the establishment of the arrhythmogenic substrate at the atrial level.
2. Detailed characterization of the progressive and unresolved inflammatory profile that causes atrial arrhythmogenesis in an in vivo model of right heart disease.
3. Identification and pharmacological targeting of pro-fibrillatory inflammatory signalling pathways, involved in the onset, maintenance, and aggravation of AF.
4. Understanding the impact of aging, sex-associated biological differences, and environmental factors in the development of atrial arrhythmogenic inflammatory status, especially in the context of right and left heart disease.
Dr. Hiram's laboratory is an equitable, diverse, and inclusive environment where he encourages recruiting and training students and trainees inspired by his research objectives. He motivates and supervises them rigorously until they obtain their degree and supports them throughout their scientific career.
Right heart failure