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Prophylactic antibiotic therapy card
Antibacterial prophylaxis for theprevention of
endocarditis
|
Condition
|
Antibiotic
|
Dosage
|
|
1 - Dental procedures/oropharyngeal and
respiratory
|
|
Standard general prophylaxis
|
Amoxicillin
|
2g PO 1 hour before the procedure
|
|
PO impossible
|
Ampicillin
|
2g IM/IV in the 30 min. prior to the
procedure
|
|
Allergy to penicillins
|
Clindamycin
or
|
600mg PO 1 hour before the
procedure
|
|
Allergy to penicillins
|
Cephalexin**
or
|
2g PO 1 hour before the procedure
|
|
Allergy to penicillins
|
Azithromycin
or
Clarithromycin |
500mg PO 1 hour before the
procedure
|
|
Allergy to penicillins and
PO impossible
|
Clindamycin
or
|
600mg IV in the 30 min. prior to the
procedure
|
|
Allergy to penicillins and
PO impossible
|
Cefazolin**
|
1g IM/IV in the 30 min. prior to the
procedure
|
|
2 - Genitourinary/gastrointestinal
procedures
|
|
High-risk patients
|
Ampicillin + Gentamicin
|
Ampicillin 2g IM/IV plus gentamicin 1.5
mg/kg (maximum 120 mg) in the 30 min. prior to the
procedure
AND
ampicillin 1g IM/IV
OR amoxicillin 1g PO 6 hours
later
|
|
High-risk patients allergic to
penicillins
|
Vancomycin + Gentamicin
|
Vancomycin 1g IV plus gentamicin 1.5 mg/kg
IV (maximum 120mg); perfusions must be completed in
the 30 min. prior to the procedure
|
|
Moderate-risk patients
|
Amoxicillin
or
Ampicillin |
Amoxicillin 2g PO 1 hour before the
procedure
OR
ampicillin 2g IM/IV in the 30 min.
prior to the procedure
|
|
Moderate
-risk patients allergic to penicillins
|
Vancomycin
|
Vancomycin 1g IV; the perfusion must be
completed in the 30 min. prior to the procedure
|
** Cephalosporins should not be used if the
allergy to penicillins displays itself as anaphylactic shock,
angioedema or urticaria.
